Sulphotransferase1A (SULT1A1) are the enzymes present in liver and scalp plays an important role in minoxidil metabolism. In India almost 50% of people are unable to produce sufficient SULT1A1 enzyme. Minoxidil is the only FDA approved drug used to treat Androgenic Alopecia. Doctors are prescribing minoxidil to treat hair regrowth and prevent hair loss. But, doctors are observing variability in response to minoxidil treatment even using for long time. Minoxidil is a prodrug and is inactive. It should be activated into minoxidil sulphate by sulphotransferase1A. People with sufficient sulphotransferase enzyme will respond well to minoxidil for hair loss treatment. Hair regrowth can be observed in minoxidil responders after continuous application for 26 weeks.
People with low sulphotransferase enzyme cannot convert inactive minoxidil into active minoxidil sulphate. So, they will not respond to minoxidil treatment. Sulphotransferase levels will be regulated by SULT1A1 gene. Mutations in the promoter region of SULT1A1 gene will leads to altered production of sulphotransferase.
Minoxidil will take minimum six to eight months to see the response. Now no need to wait for such a long time to see the response. Indian based startup company TrichoGene introduced Minoxidil Response Test which tell about the minoxidil response. MRT is a pharmacogenetics test that analyses SULT1A1 gene mutation with 100% accuracy.MRT is backed by strong scientific evidence and research. Founders of Trichogene Dr.M. Sai Babu and Mohd.Rizwan Younus said that “we are providing expensive pharmacogenetic test for very affordable price and made it available to common man who are looking for better hair loss treatment”.
One can order MRT from www.trichogene.in. You will receive MRT kit to your doorstep. Collect simple saliva sample and send back to lab by following instructions given in the kit insert. Your sample will be analysed, and results will be sent in 7 working days. It is the most affordable test and helps doctors to provide more precise and precision treatment for hair loss.